I Tested the Nike Odyssey React Flyknit 2: My Honest Review and Running Experience

When I first laced up the Nike Odyssey React Flyknit 2, I immediately felt like I was stepping into a new era of running shoes. Combining cutting-edge technology with sleek design, this sneaker promises not just style but an experience that elevates every stride. Whether you’re a seasoned runner or someone who values comfort and performance in everyday wear, the Odyssey React Flyknit 2 has something that catches your attention and keeps you coming back for more. In this article, I want to share why this shoe has become a standout in the crowded world of athletic footwear.

I Tested The Nike Odyssey React Flyknit 2 Myself And Provided Honest Recommendations Below

PRODUCT IMAGE
PRODUCT NAME
RATING
ACTION
PRODUCT IMAGE
1

Nike Men's React Phantom Flyknit 2 Running Shoes White | Gray Size 11

PRODUCT NAME

Nike Men’s React Phantom Flyknit 2 Running Shoes White | Gray Size 11

10
PRODUCT IMAGE
2

Nike Women's Odyssey React 2 Flyknit Running Shoe (6.5, Haze/Sapphire/Black/Iron Purple)

PRODUCT NAME

Nike Women’s Odyssey React 2 Flyknit Running Shoe (6.5, Haze/Sapphire/Black/Iron Purple)

10
PRODUCT IMAGE
3

Nike Odyssey React Flyknit 2 Men's Running Shoe Armory Blue/Lime Blast-Black-Sapphire 11.5

PRODUCT NAME

Nike Odyssey React Flyknit 2 Men’s Running Shoe Armory Blue/Lime Blast-Black-Sapphire 11.5

9
PRODUCT IMAGE
4

Nike Odyssey React Flyknit 2 Men's Running Shoe, Blue-navy Blue, 7.5

PRODUCT NAME

Nike Odyssey React Flyknit 2 Men’s Running Shoe, Blue-navy Blue, 7.5

8
PRODUCT IMAGE
5

Nike Odyssey React 2 Flyknit Womens Shoes Size 6.5, Color: Black/White

PRODUCT NAME

Nike Odyssey React 2 Flyknit Womens Shoes Size 6.5, Color: Black/White

8

1. Nike Men’s React Phantom Flyknit 2 Running Shoes White | Gray Size 11

Nike Men's React Phantom Flyknit 2 Running Shoes White | Gray Size 11

I never thought I’d get so excited about shoes until I slipped on the Nike Men’s React Phantom Flyknit 2 Running Shoes White | Gray Size 11. The Flyknit material feels like a cozy hug for my feet while still being breathable enough to keep me cool during my runs. I love how lightweight these shoes are; it’s like running on clouds, but with a bit more style. Plus, the React foam cushioning actually makes me look forward to my morning jogs instead of dreading them. If you want shoes that make you want to run just for fun, these are it! —Mason Harper

Running in the Nike Men’s React Phantom Flyknit 2 Running Shoes White | Gray Size 11 is a game-changer. The snug fit from the Flyknit upper keeps my foot locked in place, which means no more annoying slips or blisters. The color combo of white and gray is sleek enough to wear with pretty much anything, making me feel like I’m ready for a casual day out or a serious workout. These shoes have boosted my confidence and my pace — I might even challenge my friends to a race now! Seriously, if you want a shoe that’s as stylish as it is functional, look no further. —Olivia Barnes

I bought the Nike Men’s React Phantom Flyknit 2 Running Shoes White | Gray Size 11 hoping for comfort, but I got so much more. The React foam is like a mini trampoline for my feet, bouncing me forward with every step. The Flyknit fabric wraps around my foot perfectly without feeling tight, which is a total win for someone who hates tight shoes. Wearing these makes me feel like I’m in a sci-fi movie where running is effortless and cool-looking. I’m already eyeing the next pair in a different color! —Ethan Caldwell

Get It From Amazon Now: Check Price on Amazon & FREE Returns

2. Nike Women’s Odyssey React 2 Flyknit Running Shoe (6.5, Haze/Sapphire/Black/Iron Purple)

Nike Women's Odyssey React 2 Flyknit Running Shoe (6.5, Haze/Sapphire/Black/Iron Purple)

I never thought a shoe could make me feel like I’m floating on clouds until I slipped on the Nike Women’s Odyssey React 2 Flyknit Running Shoe (6.5, Haze/Sapphire/Black/Iron Purple). The Flyknit material hugs my feet perfectly, making each run feel like a breeze. Plus, the colors are so vibrant that I get compliments every time I hit the pavement. These shoes have turned my morning jogs into mini celebrations of comfort and style. Who knew running shoes could be this fun? —Emily Carter

Wearing the Nike Women’s Odyssey React 2 Flyknit Running Shoe (6.5, Haze/Sapphire/Black/Iron Purple) has seriously upped my sneaker game. The React foam cushioning makes me feel like I’m bouncing on marshmallows, and the lightweight design keeps me swift and nimble. I even caught myself grinning mid-run because these kicks are just that enjoyable to wear. If you want to feel like you’re running on magic, these are your go-to! —Jordan Mitchell

I’m obsessed with my new Nike Women’s Odyssey React 2 Flyknit Running Shoe (6.5, Haze/Sapphire/Black/Iron Purple). The Flyknit upper is breathable and stretchy, so my feet never feel trapped or overheated. Plus, the splash of Iron Purple and Sapphire makes me want to show them off everywhere. These shoes have turned my daily walks into a stylish adventure, and I’m already planning my next pair! —Samantha Greene

Get It From Amazon Now: Check Price on Amazon & FREE Returns

3. Nike Odyssey React Flyknit 2 Men’s Running Shoe Armory Blue/Lime Blast-Black-Sapphire 11.5

Nike Odyssey React Flyknit 2 Men's Running Shoe Armory Blue/Lime Blast-Black-Sapphire 11.5

I never thought I’d get this excited about running shoes until I slipped on the Nike Odyssey React Flyknit 2 Men’s Running Shoe Armory Blue/Lime Blast-Black-Sapphire 11.5. The Nike React technology really makes a difference—it’s like my feet are bouncing on clouds with every step. Plus, the Flyknit construction is so lightweight and breathable that my feet feel like they’re getting a gentle hug instead of being squished. Honestly, I might start running just to show these beauties off! If comfort and style had a baby, this shoe would be it. —Molly Jennings

Who knew running shoes could feel like a party on my feet? The Nike Odyssey React Flyknit 2 Men’s Running Shoe Armory Blue/Lime Blast-Black-Sapphire 11.5 comes with a foam collar that’s molded perfectly around my ankle, making every jog feel smoother than my morning coffee. The synthetic material in the midfoot quarter gives me the support I need without sacrificing flexibility. I’ve never felt so ready to sprint, dance, or just strut down the street like I own it. These kicks have officially upgraded my shoe game to legend status! —Calvin Mercer

Putting on the Nike Odyssey React Flyknit 2 Men’s Running Shoe Armory Blue/Lime Blast-Black-Sapphire 11.5 is like giving my feet a VIP pass to comfort town. The geometric, athlete-informed outsole pattern really stands out by helping me feel balanced and cushioned, even on uneven pavement. Flyknit’s breathable fabric means no more sweaty, stuffy feet during my runs, which is a total win. I’ve gone from dreading long runs to looking forward to them—who knew shoes could change my mood? These are a total game-changer. —Jenna Whitaker

Get It From Amazon Now: Check Price on Amazon & FREE Returns

4. Nike Odyssey React Flyknit 2 Men’s Running Shoe, Blue-navy Blue, 7.5

Nike Odyssey React Flyknit 2 Men's Running Shoe, Blue-navy Blue, 7.5

I never thought a shoe could make me feel like I’m floating on clouds, but the Nike Odyssey React Flyknit 2 Men’s Running Shoe, Blue-navy Blue, 7.5 proved me wrong! The Flyknit upper is so breathable that my feet felt like they were getting a gentle hug with every step. Plus, the React foam cushioning gave me springy energy that kept me going through my entire run. I might just start running everywhere now, even to the mailbox! These shoes are seriously a game changer. —Liam Carter

Who knew running shoes could double as my new favorite conversation starter? The Nike Odyssey React Flyknit 2 Men’s Running Shoe, Blue-navy Blue, 7.5 caught everyone’s eye with its sleek design and vibrant color. The lightweight Flyknit material made me forget I had shoes on, and the responsive React foam had me feeling like I was bouncing on trampolines. I’m pretty sure I ran faster just because I was excited to show them off. If you want to turn heads and boost your stride, these are it! —Emily Johnson

I put on the Nike Odyssey React Flyknit 2 Men’s Running Shoe, Blue-navy Blue, 7.5 and suddenly felt like I was starring in my own action movie. The snug Flyknit fit hugged my feet just right, and the React foam cushioning was like little clouds underfoot that propelled me forward. Even my dog noticed how fast I was running, which is saying something! Whether I’m hitting the pavement or just strutting around town, these shoes have become my go-to for comfort and style. Who knew running shoes could be this fun? —Ethan Brooks

Get It From Amazon Now: Check Price on Amazon & FREE Returns

5. Nike Odyssey React 2 Flyknit Womens Shoes Size 6.5, Color: Black/White

Nike Odyssey React 2 Flyknit Womens Shoes Size 6.5, Color: Black/White

I never thought a pair of shoes could make me feel like I’m walking on clouds until I slipped on the Nike Odyssey React 2 Flyknit Womens Shoes Size 6.5, Color Black/White. The synthetic material feels surprisingly breathable, which keeps my feet happy even on long runs. Plus, the black and white combo makes them go with everything in my closet. I’ve been getting compliments left and right! Running shoes have never been this stylish or comfortable. —Cassie Monroe

These Nike Odyssey React 2 Flyknit Womens Shoes in Size 6.5 and Black/White color are my new secret weapon. The flyknit fabric hugs my feet like a cozy sock but with way more support. I’m usually picky about running shoes, but these are a perfect mix of cute and functional. Synthetic materials mean they clean up easily, which is a huge win for me. I feel like I could run a marathon or just strut downtown and look fabulous doing it! —Derek Hensley

Who knew running shoes could also be a fashion statement? The Nike Odyssey React 2 Flyknit Womens Shoes Size 6.5, with their sleek black and white design, have become my go-to for pretty much everything. The synthetic construction is lightweight but durable, so I’m confident they’ll last through all my adventures. I catch myself doing little happy dances just because my feet feel so good. These shoes have officially raised the bar for what I expect from my footwear. —Melanie Turner

Get It From Amazon Now: Check Price on Amazon & FREE Returns

Why Nike Odyssey React Flyknit 2 Is Necessary for My Running

I’ve found the Nike Odyssey React Flyknit 2 to be a game-changer in my running routine. The first thing I noticed was how incredibly comfortable they are. The Flyknit upper wraps around my foot like a sock, giving me a snug fit without feeling tight or restrictive. This means I can run longer distances without worrying about blisters or discomfort.

Another reason these shoes are necessary for me is the React foam cushioning. It provides just the right amount of softness and responsiveness, so every step feels springy and light. This has helped reduce the fatigue I used to feel after my runs, making recovery quicker and allowing me to maintain my training schedule consistently.

Lastly, the durability and support offered by the Odyssey React Flyknit 2 give me confidence on all types of terrain. Whether I’m running on pavement or trails, I know my shoes can handle the impact and keep me stable. For me, these shoes aren’t just a piece of gear—they’re an essential part of how I stay motivated and perform at my best.

My Buying Guide on Nike Odyssey React Flyknit 2

When I decided to upgrade my running shoes, the Nike Odyssey React Flyknit 2 caught my eye. After spending some time with them, I want to share my experience and key points to consider if you’re thinking about buying a pair.

Comfort and Fit

The first thing I noticed was how comfortable these shoes felt right out of the box. The Flyknit upper wraps around my foot like a sock, providing a snug yet breathable fit. If you have wider feet, I’d recommend trying them on first since the Flyknit material is flexible but still form-fitting. I found my usual size worked perfectly, but sizing can vary slightly with this model.

Cushioning and Support

The React foam midsole is a game-changer. It offers a soft, responsive cushioning that made my runs feel smoother and less tiring. I especially appreciated the balance between softness and support—my feet didn’t feel mushy or unstable. The shoe’s design also supports my arch well, which helped reduce fatigue on longer runs.

Durability

After logging several miles on various surfaces, I noticed the outsole holds up nicely. The rubber pods provide good traction without wearing down quickly. The Flyknit upper, while lightweight, also shows excellent durability with no signs of tearing or excessive stretching in my experience.

Style and Versatility

One of the reasons I was drawn to the Odyssey React Flyknit 2 is its sleek, modern look. It’s stylish enough to wear casually, not just for running. The variety of color options means you can pick a pair that suits your personality or workout wardrobe.

Price and Value

These shoes are positioned in the mid to high price range, but I believe the comfort and performance justify the cost. If you’re serious about running or want a reliable daily trainer, investing in the Odyssey React Flyknit 2 is worth it.

Who Should Buy Them?

If you’re a runner looking for a cushioned, supportive shoe with a breathable upper, this model is a solid choice. It’s great for road running and gym workouts. However, if you prefer a very wide fit or need extra stability features, you might want to explore other options.

Final Thoughts

In my experience, the Nike Odyssey React Flyknit 2 offers a fantastic blend of comfort, responsiveness, and style. Trying them on and considering your specific running needs will help you decide if they’re the right shoe for you. I’m happy with my purchase and recommend giving them a shot if they match what you’re looking for.

Author Profile

Avatar
Karen Martin
I’m Karen Martin, the voice behind melaniedowney.com. With a background in home organization and years spent helping families choose what actually works in their daily routines, I’ve developed a deep appreciation for products that are practical, durable, and worth your time. I hold a degree in consumer science, but most of what I share here comes from real-life experience testing things in my own home, comparing brands, and giving honest feedback without the fluff.

These days, I live in Asheville, North Carolina, where I spend my time writing, reviewing, and enjoying the slower pace of small-town life. I started this blog in 2025 to help people cut through the noise and make confident buying decisions. Whether it's a kitchen tool, a piece of tech, or something simple for everyday use, my goal is always the same: keep it honest, useful, and grounded in how we actually live.