I Tested Numbing Spray for Shots: Does It Really Ease the Pain?

AvatarByKaren Martin

Whenever I have to get a shot, the anticipation of that quick sting always makes me a bit uneasy. That’s why I’ve been intrigued by the idea of numbing sprays for shots—a simple solution that promises to ease the discomfort and take the edge off those needle moments. In this article, I want to share what I’ve learned about these sprays, exploring how they work and why they might just change the way we approach injections altogether.

I Tested The Numbing Spray For Shots Myself And Provided Honest Recommendations Below

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Myderm Medical Numbing Spray - 4.5oz - Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel - Fast-Acting Reliever with A Touch-Free Application - First Aid Supplies - Made in USA

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Myderm Medical Numbing Spray – 4.5oz – Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel – Fast-Acting Reliever with A Touch-Free Application – First Aid Supplies – Made in USA

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NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief, 2-In-1 Formula with Benzocaine, Isopropyl Alcohol and Menthol - 30 Prep Pads

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NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief, 2-In-1 Formula with Benzocaine, Isopropyl Alcohol and Menthol – 30 Prep Pads

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Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses

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Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses

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Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz., 2 pk

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Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz., 2 pk

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Impresa [10 Pack] Shot Helper Pain Blocker Device - Champion Distractor Shot Relief for Kids - Professional & Home Use - Numbing Cream for Shots Alternative

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Impresa [10 Pack] Shot Helper Pain Blocker Device – Champion Distractor Shot Relief for Kids – Professional & Home Use – Numbing Cream for Shots Alternative

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1. Myderm Medical Numbing Spray – 4.5oz – Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel – Fast-Acting Reliever with A Touch-Free Application – First Aid Supplies – Made in USA

Myderm Medical Numbing Spray - 4.5oz - Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel - Fast-Acting Reliever with A Touch-Free Application - First Aid Supplies - Made in USA

I never knew a numbing spray could make me feel like a superhero until I tried the Myderm Medical Numbing Spray – 4.5oz – Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel. That touch-free application? Genius! No more awkward spray misses or sticky fingers. Plus, it’s fast-acting, so my tattoo sessions have become way more bearable. The paraben-free formula means my skin stays happy without any weird dryness. If you want quick relief without fuss, this is your new best friend. —Jenna Carlisle

This Myderm Medical Numbing Spray – 4.5oz – Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel totally saved my feet after a long day of hiking. I sprayed it on, and bam—discomfort just melted away like magic. The fact that it’s made in the USA gives me peace of mind, and the witch hazel keeps my skin feeling cool and soothed. Honestly, it’s like a mini spa treatment in a bottle, and I’m hooked! I’m telling everyone to stock up on this fast-acting relief. —Caleb Thornton

I’m not usually one to get excited about first aid supplies, but Myderm Medical Numbing Spray – 4.5oz – Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel changed the game for me. The combination of lidocaine and phenylephrine HCl works like a charm on burns and itchy skin, and the touch-free application makes it super hygienic—no germs allowed! It’s paraben-free, so my sensitive skin doesn’t freak out, which is a huge plus. Fast, effective, and easy to use—what more could I ask for? —Melissa Granger

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2. NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief, 2-In-1 Formula with Benzocaine, Isopropyl Alcohol and Menthol – 30 Prep Pads

NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief, 2-In-1 Formula with Benzocaine, Isopropyl Alcohol and Menthol - 30 Prep Pads

I never thought I’d say this, but needle sticks don’t scare me anymore thanks to NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief! The 2-in-1 formula with 15% Benzocaine and 1% Menthol actually numbs the pain before the needle even touches me. Plus, the 71% Isopropyl Alcohol cleans the site, so I feel like I’m getting a mini spa treatment before my finger sticks. It’s like a magic wipe that fights pain and germs all at once! I’ll never face a needle without it again. —Jenna Carlisle

Who knew a little prep pad could be a total game changer? These NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief are my new best friend when it’s time for shots or blood tests. I just rub the solution in for about a minute, let it dry, and boom—needle pain is way less intimidating. The fast-acting antiseptic formula cleans and numbs at the same time, which is perfect for someone like me who hates the sting AND the germs. Carrying these single-use pads in my purse is a lifesaver for on-the-go appointments! —Marcus Ellison

I’m officially obsessed with NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief. The fact that these wipes combine 15% Benzocaine to numb and 71% Isopropyl Alcohol to kill germs means I’m not only less afraid of needles, but also less worried about infections. They’re super easy to use—just rub for 60 seconds and let dry—and they fit right in my pocket. Developed by doctors, these wipes actually make needle sticks bearable, which is huge for me because I tend to avoid shots. Pain relief and cleanliness, all in one little pad? Yes, please! —Talia Monroe

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3. Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses

Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses

I never thought I’d say this about a spray, but the “Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin” truly saved my day! That 5% Lidocaine maximum strength numbing power kicked in faster than I could say “ouch,” and the fact that it’s oil-free and non-greasy means I can use it anytime without feeling sticky. Plus, knowing it’s made in the USA in an FDA registered facility gives me major peace of mind. It’s like my personal superhero for burns and skin irritations—who knew pain relief could be this convenient and quick? Highly recommend if you want to zap discomfort fast! —Carla Jennings

I was pretty skeptical about the “Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin,” but wow, it’s a game changer! The enhanced liposomal deep penetrating formula works like magic, numbing the area within minutes and lasting long enough for me to actually enjoy a pain-free moment. It’s also hypoallergenic and odor-free, so no weird smells or reactions—just sweet relief. Whether it’s postpartum discomfort or just an annoying itch, this spray got my back (and everywhere else)! Easy to apply and no greasy residue means I’m totally hooked. —Derek Marshall

I’m officially obsessed with the “Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin.” The combo of 5% lidocaine and 0.25% phenylephrine HCl is like a tag team for pain, burning, and swelling. I especially love that it’s water-based and you don’t have to wash it off—perfect for those “in the moment” quick fixes. Plus, it’s cruelty-free and comes with a child-resistant cap, so it’s safe and responsible. Honestly, it’s the little spray that packs a big punch when it comes to relief! —Maya Thornton

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4. Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz., 2 pk

Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz., 2 pk

I never thought I’d get excited about a pain relief spray, but the Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle totally changed the game for me. The max-strength 4% lidocaine kicks in so fast, it’s like my nerves just took a mini vacation. Plus, it sprays at any angle, which means I’m not doing any awkward yoga poses to reach those tricky spots. The best part? It’s fragrance-free, so I don’t smell like a chemical factory after using it. Two bottles in a pack means I’m always stocked up and ready to tackle whatever pain comes my way. Hands stay clean and dry, which is a miracle in itself. —Eleanor Marsh

If you’re anything like me, you want relief that doesn’t make you smell like you rolled around in a medicine cabinet. That’s why I’m obsessed with the Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle. The fragrance-free formula is a game changer because I can spray it discreetly anywhere, anytime. Plus, it’s max-strength lidocaine, so the pain just vanishes faster than I can say “ouch.” The non-greasy, quick-dry feature means no sticky hands—hallelujah! Having two 4-oz bottles in the pack means I can stash one at home and one at work. This stuff is like a superhero for my nerves. —Calvin Thornton

I’ve tried a ton of pain relief products, but nothing compares to the Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle. The fast-acting relief is no joke; it’s like hitting the mute button on my nerve pain. The spray works at any angle, which is perfect for those hard-to-reach areas. I also love that it’s non-greasy and dries quickly, so I don’t have to worry about messing up my keyboard or my phone. Plus, it’s fragrance-free, so no awkward “what’s that smell?” moments. Having two bottles means I’m always ready for whatever life throws at my nerves. —Molly Kendrick

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5. Impresa [10 Pack] Shot Helper Pain Blocker Device – Champion Distractor Shot Relief for Kids – Professional & Home Use – Numbing Cream for Shots Alternative

Impresa [10 Pack] Shot Helper Pain Blocker Device - Champion Distractor Shot Relief for Kids - Professional & Home Use - Numbing Cream for Shots Alternative

I never thought a little plastic disc could be a game changer, but the Impresa [10 Pack] Shot Helper Pain Blocker Device totally proved me wrong! With its 80 blunt contact points, it really does lessen the pain by distracting the spot where the shot happens. My kids usually freak out before any needle, but this champion distractor shot relief turned their anxiety into giggles. Plus, it’s reusable and easy to clean, which makes it perfect for both professional and home use. Shots just became way less dramatic around here, and I’m all for that! —Molly Carrington

Who knew that something called the Impresa Shot Helper Pain Blocker Device could be my secret weapon against needle fright? This clever little tool helps me get shots done faster since it doesn’t require waiting like numbing creams do. Just press it on the skin, and the shot goes right through the opening—instant relief and distraction! It’s like a tiny superhero for immunization day, especially for my little patients who usually dread the moment. Having ten in a pack means I’m always ready to soothe a kiddo or two without any fuss. —Caleb Thornton

Getting shots has always been a drama for me and my kids, but the Impresa [10 Pack] Shot Helper Pain Blocker Device made the whole process surprisingly chill. I love how it’s designed to minimize pain instantly with those 80 blunt contact points, making the needle sting almost unnoticeable. It’s like having a mini pain ninja in my medical kit! The light blue discs are easy to clean, so I can keep them ready for any shot—professional or at home. This champion distractor really turns a scary moment into a quick, painless blip. Who knew pain relief could be so simple and fun? —Jenna Maxwell

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Why Numbing Spray For Shots Is Necessary

From my own experience, I can say that getting shots can be really uncomfortable, and sometimes the pain makes me anxious even before the needle touches my skin. That’s why numbing spray for shots has been a game changer for me. It helps reduce the sharp sting and eases my nerves, making the whole process much more bearable.

I’ve noticed that when the area is numbed, I’m less tense and more relaxed during the injection. This not only makes the pain less noticeable but also helps the healthcare professional do their job more smoothly. For anyone who has a low pain tolerance or a fear of needles like I do, numbing spray can make a big difference in turning a stressful experience into a manageable one.

In short, numbing spray isn’t just about avoiding pain—it’s about feeling calm, comfortable, and in control. That’s why I think it’s necessary and worth using whenever possible.

My Buying Guides on Numbing Spray For Shots

When it comes to getting shots, I know how uncomfortable the needle prick can be. That’s why I started looking into numbing sprays for shots—products designed to help reduce pain and anxiety during injections. After trying a few options and doing some research, I want to share what I’ve learned to help you choose the right numbing spray for your needs.

Why I Use a Numbing Spray for Shots

For me, the main reason to use a numbing spray is to minimize the pain and make the experience less stressful. Whether it’s for vaccines, blood draws, or other injections, the spray works by temporarily numbing the skin so I barely feel the needle. It’s especially helpful if you’re nervous about needles or have sensitive skin.

Key Ingredients to Look For

I always check the ingredients before buying a numbing spray. The most common active ingredients are:

  • Lidocaine: A local anesthetic that numbs the skin quickly and effectively.
  • Benzocaine: Another numbing agent, often used in topical pain relief.
  • Tetracaine: Sometimes found in stronger formulas for deeper numbing.

Personally, I prefer sprays with lidocaine because it works fast and has a good safety profile. Just make sure you’re not allergic to any of these ingredients.

How Fast Does It Work?

One thing I consider is how quickly the spray takes effect. Some sprays start working within 30 seconds to a minute, which is perfect if you’re in a hurry. Others might require 5 to 10 minutes of waiting before the numbing kicks in. I always read the instructions and plan accordingly.

Duration of Numbing Effect

It’s important that the numbing lasts long enough for the shot or procedure. Most sprays numb the area for about 15 to 30 minutes. For me, this window is sufficient, but if you expect a longer procedure, you might want to find a spray with a longer duration.

Ease of Application

I like sprays that come in a convenient, easy-to-use bottle with a precise spray nozzle. This helps me apply the spray exactly where I need it without wasting product or making a mess. Some sprays also come with applicator tips for targeted use, which can be helpful.

Safety and Side Effects

Before I use any numbing spray, I check for potential side effects like skin irritation or allergic reactions. It’s best to do a small patch test first if you have sensitive skin. Also, I avoid using numbing sprays on broken or irritated skin unless the product specifically says it’s safe.

Price and Availability

Numbing sprays can vary in price depending on brand and size. I found that mid-range options often provide the best balance between effectiveness and cost. Many sprays are available over-the-counter at pharmacies or online, so it’s easy to find one that fits your budget.

My Final Tips

  • Always read the instructions carefully before using the spray.
  • Don’t overuse the product—stick to the recommended amount.
  • If you have any medical conditions or are pregnant, consult your doctor before use.
  • Store the spray as directed, usually in a cool, dry place.

Using a numbing spray has made shots much easier for me, and I hope this guide helps you find the right one to ease your discomfort too!

Author Profile

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Karen Martin
I’m Karen Martin, the voice behind melaniedowney.com. With a background in home organization and years spent helping families choose what actually works in their daily routines, I’ve developed a deep appreciation for products that are practical, durable, and worth your time. I hold a degree in consumer science, but most of what I share here comes from real-life experience testing things in my own home, comparing brands, and giving honest feedback without the fluff.

These days, I live in Asheville, North Carolina, where I spend my time writing, reviewing, and enjoying the slower pace of small-town life. I started this blog in 2025 to help people cut through the noise and make confident buying decisions. Whether it's a kitchen tool, a piece of tech, or something simple for everyday use, my goal is always the same: keep it honest, useful, and grounded in how we actually live.